A research team led by Zhen-Xing Endowed Professor Jian Yang at the School of Life Sciences, Westlake University, has ...

Since the completion of the Human Genome Project, single linear reference genomes (such as GRCh38) have served as the foundation for biomedical research. However, the genetic backgrounds of human ...

A new software package called CREsted, published in Nature Methods, gives researchers an end-to-end workflow for modeling and ...

Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals alone, you'll miss all the dialog. With sound alone, you will miss the ...

Next-generation sequencing (NGS), especially long-read DNA sequencing, is transforming infectious organism detection by ...

A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and efficiently read DNA containing non-standard bases—a task once thought too ...

MethylScan is a new low-cost cell-free DNA methylome test that removes much of the healthy blood DNA background, helping rare ...

Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...

A new DNA sequencing technique that delivers faster and more accurate bacterial infection diagnoses could be implemented nationwide. The method, developed by the Medicines and Healthcare products ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...