When treated with KRAS inhibitors alone, cancer cells can escape destruction by using the salvage pathway to gather ...

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States Graduate Group in Biochemistry, Biophysics, and ...

School of Chemistry and Molecular Biology, University of Queensland, Brisbane, Australia Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States In ...

Researchers at Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that a new target of rapamycin (TOR) inhibitor, ...

Researchers from Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that new TOR inhibitor rapalink-1 prolongs ...

Cationic CDs, which possess a positively charged surface, have shown the ability to mimic natural enzyme applications. The positive charge on the surfaces of these nanomaterials significantly ...

Proteases, a class of enzymes that play critical roles in health and disease, exert their function through the cleavage of peptide bonds. Identifying substrates that are efficiently and selectively ...

Abstract: Protein structure based enzyme class prediction is a useful and challenging task in protein analysis. Here we describe a new method for the prediction of enzyme class based on Rough Sets ...